3 edition of Vinyl chloride toxicity found in the catalog.
Vinyl chloride toxicity
by U.S. Dept. of Health & Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry in Atlanta, GA
Written in English
|Statement||guest contributors, Robert Harrison, Gloria Hathaway ; guest editors, Laura Welch, Carlo Tamburro|
|Series||Case studies in environmental medicine -- 2|
|Contributions||Hathaway, Gloria J, Welch, Laura S, Tamburro, Carlo, United States. Agency for Toxic Substances and Disease Registry, DeLima Associates|
|The Physical Object|
|Number of Pages||21|
Vinyl chloride monomer (VCM) is one of the world’s most important and largest commodity chemicals. VCM is used primarily for the production of polyvinyl chloride (PVC) homopolymer and copolymer resins. PVC has the advantage of being utilized in conversion and fabrication processes with great flexibility, such that end products cover a wide. Keith G. Tolman, Anthony S. Dalpiaz, in Drug-Induced Liver Disease (Third Edition), Vinyl Chloride. Vinyl chloride is an organochloride, flammable gas with a sickly sweet odor, which is a colorless at ambient temperature. Discovered in , it is used as an intermediate in the production of polyvinyl chloride (PVC), which is molded into PVC piping and bottles.
5. Vinyl Chloride 1. Acute Exposure Guideline Levels. PREFACE. Under the authority of the Federal Advisory Committee Act (FACA) P.L. of , the National Advisory Committee for Acute Exposure Guideline Levels for Hazardous Substances (NAC/AEGL Committee) has been established to identify, review, and interpret relevant toxicologic and other scientific data and develop AEGLs for high. The micronucleus assay was performed in the peripheral lymphocytes of 32 subjects occupationally exposed to vinyl chloride monomer (VCM) divided into two groups according to years of employment. Blood samples were taken in the period from 24 h to 90 days following a .
Polyvinyl chloride (PVC or vinyl) is the most toxic plastic for our health and the environment. For more than 30 years, leading health, environmental justice, and health-impacted organizations across the country and world have been campaigning to phase out this poison plastic. Vinyl chloride is also a product of anaerobic degradation of chlorination solvents such as would be expected to occur in groundwater and landfills. Small quantities of vinyl chloride can be released to food by migration of vinyl chloride monomer present in polyvinyl chloride food wrappings and containers.
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Etiology. Vinyl chloride toxicity occurs mainly through occupational exposure during the polymerization of VCM into PVC; however, community exposures secondary to industrial spills have occurred.
Additionally, there are reports of cases of significant chronic exposure related to aerosol propellant usage in the s and early s, although VCM is no longer utilized in this : Matthew S. Fralish, John W. Downs. Vinyl chloride is a chemical intermediate, not a final product.
Due to the hazardous nature of vinyl chloride to human health there are no end products that use vinyl chloride in its monomer form. Polyvinyl chloride (PVC) is very stable, storable, and nowhere near as acutely toxic as the vinyl chloride monomer (VCM).Chemical formula: C₂H₃Cl.
What is vinyl chloride. Vinyl chloride is a colorless gas that burns easily. It does not occur naturally and must be produced industrially for its commercial uses. Vinyl chloride is used primarily to make polyvinyl chloride (PVC); PVC is used to make a variety of plastic products, including pipes, wire and cable coatings, and packaging materials.
Vinyl chloride, a chemical known to cause cancer, poisons the air breathed by workers and people living in contaminated communities.
Vinyl chloride is a deadly toxic chemical, despite industry’s repeated attempts to hide the threats. Vinyl chloride is used to make polyvinyl chloride. Vinyl chloride toxicity book Certain persons, such as alcoholics, have an increased risk of vinyl chloride toxicity.
During the childbearing years, women should avoid exposure since there is a possibility that vinyl chloride increases the incidence of congenital birth defects. Prenatal or early exposure to vinyl chloride may increase the risk of cancer later.
Vinyl chloride - Identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information: Note: See Working with the Information on this Page section below for important notes about this data.
Any underlined term with a book icon has additional information. Chloride Toxicity. (2) Uses Most of the vinyl chloride produced in the United States is used to make polyvinyl chloride (PVC), a material used to manufacture a variety of plastic and vinyl products including pipes, wire and cable coatings, and packaging materials.
(1) Smaller amounts of vinyl chloride are used in furniture and automobile. Toxicological Profile for Vinyl Chloride (Update).
Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. Agency for Toxic Substances and Disease Registry (ATSDR). Case Studies in Environmental Medicine. Vinyl Chloride Toxicity.
Public Health Service, U.S. Department of Health and Human Services, Atlanta, GA. The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects information for the hazardous substance described here.
Each peer-reviewed profile identifies and reviews the key literature that describes a hazardous substance's toxicologic properties. Other pertinent literature is also presented, but is described in less detail than the key studies. This table contains the most up to date criteria for aquatic life ambient water quality criteria.
Aquatic life criteria for toxic chemicals are the highest concentration of specific pollutants or parameters in water that are not expected to pose a significant risk to the majority of species in a given environment or a narrative description of the desired conditions of a water body being "free.
for the hazard and dose-response assessment in IRIS pertaining to chronic exposure to vinyl chloride. It is not intended to be a comprehensive treatise on the chemical or toxicological nature of vinyl chloride.
In Section 6, EPA has characterized its overall confidence in the quantitative and qualitative aspects of hazard and dose response. Vinyl chloride: incident management Ref: PHE publications gateway number PDF, KB, 11 pages This file may not be suitable for users of assistive technology.
The toxicity of vinyl chloride as determined by repeated exposure of laboratory animals. Am Ind Hyg Assoc J. Oct; – Viola PL, Bigotti A, Caputo A. Oncogenic response of rat skin, lungs, and bones to vinyl chloride.
Cancer Res. May; 31 (5)– Maltoni C. Occupational carcinogenesis. Predictive value of carcinogenesis. Toxicity of Vinyl Chloride-Polyvinyl Chloride. [Irving J. Selikoff] on *FREE* shipping on qualifying offers.
The amount of chlorine or vinyl going into the incinerator is not a reliable indicator of the amount of dioxin coming out.
Rather, incinerator design and operation have far more important impacts. However, in uncontrolled burning (e.g., volcanoes, forest fires, old incinerators, backyard burn barrels and accidental building fires), dioxin can. Occupational exposure to vinyl chloride has been associated with reduced sexual function in both sexes and gynecological effects in women (Makarov, ; Makarov et al., ).
For the oral route of exposure, the primary target organ of vinyl chloride toxicity in animals is the liver. Vinyl Chloride is a toxic cancer-causing chemical that is used to make PVC.
Lawsuits and class actions have recently ended in multi-million dollar settlements for vinyl chloride exposure. What You Can Do & How We Can Help. The Schmidt Firm, PLLC is currently accepting Vinyl Chloride. For the manufacture of vinyl chloride assemble a preliminary database.
This should include thermophysical data, MSDSs for each, chemical giving toxicity and flammability data the current prices of the chemicals 2.
Consider the first reaction step to make dichloroethane. COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle coronavirus.
The Law and Policy of Toxic Substances Control: A Case Study of Vinyl Chloride (RFF Press) Hardcover – March 1, by Professor David D. Doniger (Author) See all 2 formats and editions Hide other formats and editions.
Price New from Used from Author: Professor David D. Doniger. Vinyl chloride, a colourless, flammable, toxic gas belonging to the family of organohalogen compounds and used principally in making polyvinyl chloride, or PVC, a widely used plastic with numerous applications.
The major industrial preparation of vinyl chloride begins with ethylene and has two.Print book: National government publication: EnglishView all editions and formats: Rating: (not yet rated) 0 with reviews - Be the first.
Subjects: Vinyl chloride -- Physiological effect. Vinyl chloride -- Toxicology. # Vinyl Chloride--toxicity\/span>\n \u00A0\u00A0\u00A0\n schema.Vinyl chloride is a colorless gas with a mildly sweet smell that easily is not a naturally-occurring substance and must be manufactured industrially for its commercial purposes.
Vinyl chloride can be formed when other substances such as trichloroethane and trichloroethylene are broken down.